Racial disparities in depression

Racial and cultural factors still affect the diagnosis and treatment of depression in elderly Americans, despite improvements to diagnostic tools and therapies in recent decades, according to a new study.
Researchers found that elderly blacks are less likely to be diagnosed — and therefore treated — than whites or Hispanics.
About 6.6 percent of elderly people in the United States have an episode of major depression each year, making it a significant public health issue for older Americans, the Rutgers University researchers pointed out in a university news release.
If it’s left untreated or undertreated, depression can have a major negative impact on quality of life and can also complicate medical conditions that are common in elderly people, including congestive heart failure, arthritis and diabetes, Ayse Akincigil, an assistant professor in Rutgers’ School of Social Work, and colleagues explained.
The investigators analyzed data collected from nearly 34,000 Medicare beneficiaries between 2001 and 2005, and found that rates of depression diagnosis were 6.4 percent for whites, 4.2 percent for blacks, 7.2 percent for Hispanics, and 3.8 percent for other groups.
“Efforts are needed to reduce the burden of undetected and untreated depression and to identify the barriers that generate disparities in detection and treatment,” the researchers concluded.
“Promising approaches include providing universal depression screening and ensuring access to care in low-income and minority neighborhoods,” they added. “An increase in the reimbursement of case management services for the treatment of depression also may be effective.”

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Adults with facial disfigurement

Adults who were born with a severe facial disfigurement have generally good psychological adjustment, according to a small new study.
Dutch researches gave a set of psychological, physical and demographic questionnaires to 59 adults, average age 34, who were born with severe facial disfigurement caused by rare, extensive facial cleft syndromes.
The same questionnaires were also completed by 59 adults with facial disfigurement caused by traumatic injury and 120 adults with no disfigurement.
The researchers found that those born with facial disfigurement had “relatively normal” psychological functioning but they did tend to have a higher rate of problems such as anxiety and depression than those with no disfigurement.
However, adults born with facial disfigurement and those with trauma-related facial disfigurement were no more likely to have a clinical level of depression and anxiety than those without facial disfigurement.
Perhaps not surprisingly, those born with facial disfigurement had lower rates of physical problems than those with trauma-related facial disfigurement, the researchers said.
Among people born with severe facial disfigurement, problems with psychological functioning were more common among those with low self-esteem and those who were concerned about how others would judge their appearance.
That finding is an important consideration for plastic and reconstructive surgeons, the researchers said.
“Improving satisfaction with facial appearance (by surgery), enhancing self-esteem or lowering fear of negative appearance evaluation (by psychological support) may enhance long-term psychological functioning,” concluded Dr. Sarah Versnel of Erasmus University Medical Center, Rotterdam, and colleagues in a journal news release.

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Humility is a positive quality

Arrogant people are less likely than humble people to offer help to someone who needs it, new research finds.

Although personal factors (such as previous time commitments and feelings of empathy or distress) and outside influences (such as how many people are watching) come into play, humility is the biggest factor in whether someone decides to lend a helping hand, according to the study published online Jan. 2 in the Journal of Positive Psychology.

 

“The findings are surprising because in nearly 30 years of research on helping behavior, very few studies have shown any effect of personality variables on helping,” the study’s lead author, Jordan LaBouff, who collaborated on the research while a doctoral candidate at Baylor University, said in a university new release.

“The only other personality trait that has shown any effect is agreeableness, but we found that humility predicted helping over and above that,” said LaBouff, now a lecturer in psychology at the University of Maine.

“The research indicates that humility is a positive quality with potential benefits,” the study’s leader and co-author, Wade Rowatt, an associate professor of psychology and neuroscience in Baylor’s College of Arts & Sciences, stated in the news release. “While several factors influence whether people will volunteer to help a fellow human in need, it appears that humble people, on average, are more helpful than individuals who are egotistical or conceited.”

The researchers conducted three separate studies involving college students. The first study asked students to report how humble they were. Those who considered themselves to be humble generally reported being helpful as well.

In the second study, which used a measure of humility that did not rely on the participants’ own judgment, the students listened to a recording about another student who was unable to attend class due to an injury. The humble students offered more time to help this person than those who were more conceited.

Finally, students were asked to choose personality traits that applied to them as quickly as possible. Again, the students who considered themselves to be humble were more likely to offer more time to help a student in need — even more so when the pressure put on the student to help was low.

“Our discovery here is that the understudied trait of humility predicts helpfulness,” Rowatt said. “Important next steps will be to figure out whether humility can be cultivated and if humility is beneficial in other contexts, such as scientific and medical advancements or leadership development.”

 

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High blood pressure

People suffering from high blood pressure, or hypertension, who keep their blood pressure levels under control may add years to their life, a new study suggests.
In fact, those in the study who took medicine to lower their blood pressure for more than four years reduced their risk of dying from cardiovascular disease over a 20-year period, the researchers found.

“For the first time, we prove that treating high blood pressure prolongs life,” said lead researcher Dr. John Kostis, a professor of medicine & pharmacology at UMDNJ-Robert Wood Johnson Medical School in New Brunswick, N.J.
“If you take your medications for a month, you live an extra day,” he said. “One day benefit from a month of treatment sounds small, but if you start treatment at 40, for example, then you live a couple of extra years.”
Although the antihypertensive diuretic chlorthalidone was used in the study, it really doesn’t make a difference which antihypertensive one uses; the benefit in terms of life expectancy should be the same, Kostis said.
“The main thing is to take medication to get blood pressure under control,” he said. “Treat your hypertension early so you can benefit from a longer, happier life.”
The report was published in the Dec. 21 issue of the Journal of the American Medical Association.
To determine the effect antihypertensive drugs might have on extending life, Kostis and his colleagues used data from the Systolic Hypertension in the Elderly Program (SHEP) trial.
In that trial, conducted between 1985 and 1990, more than 4,000 hypertensive patients were randomly assigned to take chlorthalidone or an inactive placebo. The patients in the study were an average of 72 years of age.
Kostis noted that if chlorthalidone didn’t work, patients were given a beta blocker.
At the end of the trial, all of the patients were advised to get their hypertension treated, the researchers noted.
When Kostis’ group looked at the 22-year follow-up data in 2006, about 60 percent of the participants had died. Of these, 59.9 percent of those taking chlorthalidone had died as did 60.5 percent of those who received placebo.
The researchers found that life expectancy and survival were longer for those who received chlorthalidone during the trial compared with those given a placebo.
The gain in life expectancy, for death from any cause, linked to treating hypertension was about half a day per month of treatment, they found.
Also, people taking an antihypertensive gained about one day free from cardiovascular death per month of treatment, and had less of a chance of dying from cardiovascular disease than those who had received placebo; 28 percent versus 31 percent, respectively.
Dr. Gregg C. Fonarow, a professor of cardiovascular medicine and science at the University of California, Los Angeles, said that “hypertension is a major modifiable risk factor for heart attacks, strokes, heart failure, renal failure and premature cardiovascular death.”
Treatment of adults with elevated blood pressure with antihypertensive medications has been shown in many trials to significantly reduce the risk of fatal and nonfatal cardiovascular events, heart failure and renal failure, he said.
“However, as most trials were three to five years in duration, whether there are long-lasting effects on life expectancy from treating hypertension has not been well-studied,” Fonarow said.
This study provides further compelling evidence of the enduring benefits of treating hypertension, Fonarow said.
“With over half of the 76 million men and women in the United States who have hypertension not having their blood pressure well-controlled, improved detection, treatment and control of hypertension is imperative,” he added.

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Zocor

La simvastatina, assunta per via orale tramite il farmaco Zocor, viene rapidamente assorbita a livello gastro-intestinale e trasportata dalla vena porta al fegato. Il primo passaggio epatico per questo principio attivo e essenziale, al fine di garantire l’idrolisi della simvastatina dalla forma chimica “lattone” al rispettivo idrossiacido, metabolita attivo del farmaco. Questa sostanza, una volta terminata la sua azione terapeutica, verra successivamente escreta prevalentemente attraverso le feci. Il processo di idrolisi appena descritto riduce drasticamente la biodisponibilita del principio attivo, che solo dopo due ore raggiunge le concentrazioni plasmatiche massime, pari al 5% della dose di simvastatina assunta oralmente. Nonostante questo calo, la simvastatina risulta particolarmente efficace nel ridurre i livelli plasmatici di colesterolo LDL, esercitando la sua azione terapeutica proprio a livello epatico, dove inibisce l’enzima chiave nella sintesi del colesterolo.

Come le altre statine, infatti, la simvastatina puo inibire l’enzima HMG-CoA reduttasi, impedendo la produzione di mevalonato, un composto organico intermedio nel metabolismo del colesterolo. Di conseguenza, vista la ridotta sintesi di questo lipide, la simvastatina up-regola l’espressione dei recettori epatocitari per le LDL. In definitiva, quindi, l’aumentato uptake epatico di colesterolo LDL e la riduzione della sintesi di VLDL, garantisce una riduzione significativa dei livelli ematici di colesterolo LDL.L’importanza di Zocor nella prevenzione delle patologie cardiovascolari sembra tuttavia essere associata anche ad altri meccanismi che non vedono il diretto ed unico coinvolgimento dell’effetto ipolipemizzante, visti i vari studi in letteratura che mostrano un significativo calo della morbilita e mortalita legata agli eventi cardiovascolari in pazienti a rischio ma con livelli di colesterolo normali.

Visit site Pillole di Zocor ordine online

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Lipitor Vendita

Lipitor è un membro della classe di farmaci noti come statine e viene utilizzato per abbassare il colesterolo ematico.

Usi Droga

Lipitor è utilizzato per abbassare il colesterolo nel sangue insieme a una dieta speciale e un corretto esercizio. Essa contribuisce a ridurre nocivi delle lipoproteine a bassa densità (LDL) nel corpo.

Uso

Lipitor devono essere prese esattamente come prescritto dal medico. Ma cercare di fare al tempo stesso ogni giorno. Si può prendere con o senza un pasto.

Dose

Si dovrebbe cercare di prendere il vostro dosi tempo facendo attenzione a non perdere nessuna. Ma se si dimentica una dose, poi prenda non appena se ne ricorda. Ma sì che lo spazio che le dosi restanti di conseguenza. Non prenda una dose doppia.

Immagazzinaggio

Conservarlo a temperatura ambiente e proteggere dall’esposizione diretta alla luce e umidità.

Overdose

Rivolgersi immediatamente al medico se si sospetta un sovradosaggio.

Maggiori informazioni

Se si dispone di un fegato danneggiato, quindi consultare il proprio medico prima di iniziare il trattamento. Il farmaco può causare stordimento, vertigini, debolezza e in alcune persone. Non consumare alcol con la droga. Aumenta le probabilità di danni al fegato. Non guidi o maneggiare macchinari pesanti fino a quando non sa come reagire al farmaco.

Pillole di Lipitor ordine online

 

 

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Pillole di Levitra

Pillole di Levitra è un farmaco realizzato nel 2003 dalla Bayer che è stato creato per migliorare le erezioni e risolvere il problema dell’impotenza maschile. Levitra aiuta gli uomini affetti da disfunzione erettile ad ottenere erezioni tali da consentire un rapporto sessuale soddisfacente.

  • Risolve il problema dell’impotenza
  • Efficace per oltre l’80% dei casi
  • L’effetto dura fino a 5 – 6 ore
  • Facilmente assimilabile dall’organismo

Levitra risulta essere meno conosciuto degli altri due farmaci anti impotenza Cialis e Viagra, ma tuttavia rappresenta la scelta fatta da molti uomini che apprezzano di Levitra la minima incidenza di effetti collaterali. Un vantaggio questo dovuto ai bassi dosaggi di principio attivo presenti nel Levitra, fattore che lo rende molto apprezzato anche da chi soffre di malattie come il diabete.

Pillole di Levitra ordine online offre un consulto medico professionale gratuito grazie al quale sarà possibile ottenere la ricetta medica necessaria per l’acquisto di Levitra. La spedizione compresa nel prezzo avviene in modo discreto, con consegna discreta in sole 24/48 ore.

Levitra: come risolve il problema dell’impotenza?

Levitra, contenente il principio attivo vardenafil, è un farmaco indicato specificatamente per il trattamento della disfunzione erettile (impotenza). La sua efficacia è stata dimostrata in oltre l’ 80% dei casi, inoltre il suo basso dosaggio di principio attivo consente di ottenere erezioni migliori, con una bassa incidenza della probabilità degli effetti collaterali.

 

Quali possono essere gli effetti collaterali?

L’azienda farmaceutica Bayer ha testato Levitra su un campione di oltre 3.750 uomini in cliniche di tutto il mondo. Quando viene assunto nelle dosi consigliate, gli effetti collaterali sono minimi e passeggeri. Gli effetti collaterali più comuni del Levitra sono mal di testa e congestione nasale.

 

Chi non può assumere Levitra?

I pazienti che stanno assumento farmaci contenenti nitrati non possono assumere Levitra. Se il soggetto dovesse maturare dei dubbi circa l’assunzione o meno del farmaco è preferibile fare appello al proprio medico.

 

Perchè scegliere Levitra?

Levitra è il farmaco anti impotenza che il colosso farmaceutico Bayer ha messo appunto nel 2003. L’importanza e la storia di questa casa farmaceutica sono sinonimo di affidabilità e sicurezza. Inoltre Levitra, grazie ai suoi dosaggi ridotti di principio attivo, è mediamente più tollerato dall’organismo, e i tempi di reazione al farmaco, nell’ordine dei 25-30 minuti, permettono di non fare troppi calcoli su quando e come assumerlo prima del rapporto.

 

 

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Penile erection

Penile erection is a physiological phenomenon where the penis becomes enlarged and firm. Penile erection is the result of a complex interaction of psychological, neural, vascular and endocrine factors, and is usually, though not exclusively, associated with sexual arousal. Penile erection can also occur due to a full urinary bladder. In some males, erection can occur spontaneously at any time of day, and is known as nocturnal penile tumescence when occurring during REM sleep.

The swelling, hardening and enlargement of the penis enables sexual intercourse. The scrotum may also become tightened during an erection. In many cases, but not all, the foreskin retracts, exposing the glans. Erection is not required for all sexual activities.

After a male has ejaculated during a sexual encounter or masturbation, the erection usually ends, but this may take time depending on the length and thickness of the penis.

In the presence of mechanical stimulation, erection is initiated by the parasympathetic division of the autonomic nervous system (ANS) with minimal input from the central nervous system. Parasympathetic branches extend from the sacral plexus into the arteries supplying the erectile tissue; upon stimulation, these nerve branches release acetylcholine, which, in turn causes release of nitric oxide from endothelial cells in the trabecular arteries. Nitric oxide diffuses to the smooth muscle of the arteries (called trabecular smooth muscle[3]), acting as a vasodilating agent. The arteries dilate, filling the corpora spongiosum and cavernosa with blood.

Erection subsides when parasympathetic stimulation is discontinued; baseline stimulation from the sympathetic division of the ANS causes constriction of the penile arteries, forcing blood out of the erectile tissue. The cerebral cortex can initiate erection in the absence of direct mechanical stimulation (in response to visual, auditory, olfactory, imagined, or tactile stimuli) acting through erectile centers in the lumbar and sacral regions of the spinal cord. The cortex can suppress erection even in the presence of mechanical stimulation, as can other psychological, emotional, and environmental factors. The opposite term is detumescence.

Shape and size

Although many erect penises point upwards, it is common and normal for the erect penis to point nearly vertically upwards or nearly vertically downwards or even horizontally straight forward, all depending on the tension of the suspensory ligament that holds it in position. An erect penis can also take on a number of different shapes, ranging from a straight tube to a tube with a curvature up or down or to the left or right. An increase in penile curvature can be caused by Peyronie’s disease. This may cause physical and psychological effects for the affected individual, which could include erectile dysfunction or pain during erection. Treatments include oral medication (such as Colchicine) or surgery, which is most often reserved as a last resort.

The following table shows how common various erection angles are for a standing male. In the table, zero degrees is pointing straight up against the abdomen, 90 degrees is horizontal and pointing straight forward, while 180 degrees would be pointing straight down to the feet. An upward pointing angle is most common.

Occurrence of ErectionAngles
Angle (degrees) Percent
030 5
3060 30
6085 31
8595 10
95120 20
120180 5

Generally, the size of an erect penis is fixed throughout post-pubescent life. Its size may be increased by surgery, although penile enlargement is controversial, and a majority of men were “not satisfied” with the results, according to one study.

Erectile dysfunction

Erectile dysfunction (also known as ED or male impotence) is a sexual dysfunction characterized by the inability to develop or maintain an erection. The study of erectile dysfunction within medicine is known as andrology, a sub-field within urology.

Erectile dysfunction can occur due to both physiological and psychological reasons, most of which are amenable to treatment. Common physiological reasons include cardiovascular leakage and diabetes. Some drugs used to treat other conditions, such as lithium and paroxetine, may cause erectile dysfunction.

Erectile dysfunction, tied closely as it is to cultural notions of potency, success and masculinity, can have devastating psychological consequences including feelings of shame, loss or inadequacy. There is a strong culture of silence and inability to discuss the matter. In fact, around 1 in 10 men will experience recurring impotence problems at some point in their lives.

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